English to Russian Medical Medical: Pharmaceuticals clinical trials

Moreover, in vitro studies of net transmural flux using everted jejunal sacs demonstrated movement of [14C]thiamine HCl against a concentration gradient only when low, but not when high, thiamine concentration was used, so that the serosal to mucosal ratio became significantly greater than the initial value of one.

Pyrithiamine (2 µM), dinitrophenol (200 µM), norethylmaleimide (100 µM), and ouabain (100 µM), reduced the net transmural flux of 0.2 µM thiamine.