Glossary entry

English term or phrase:

(N-capped)

Romanian translation:

N- terminus/Amino terminus

Added to glossary by Ioana Huiban
Feb 7, 2014 08:01
10 yrs ago
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English term

(N-capped)

English to Romanian Medical Medical: Pharmaceuticals
Lactic-co-glycolic acid copolymer (N-capped) with 50% content of each of the two organic acid monomers and a molecular weight of 50KDa.
Proposed translations (Romanian)
3 N- terminus/Amino terminus

Discussion

Ioana Huiban (asker) Feb 7, 2014:
Exact de asta aveam nevoie! Mi-ai fost de mare ajutor. Multumesc ca m-ai luminat Claudia! :)
Claudia Coja Feb 7, 2014:
Within the PAS superfamily, the N-terminal segment (N-cap) is poorly conserved and its role is not well understood.
http://www.ncbi.nlm.nih.gov/pubmed/16513745
The N- and C-terminal ends of an isolated helix contain four NH donors and four CO acceptors each, respectively due to edge effects (Figure 2 ). It has been shown that hydrogen bond partners for these otherwise unsatisfied first four amide protons and last four carbonyl oxygens are often provided by polar groups that flank the helix termini. Furthermore, these residue positions were found to contain differentiated amino acid preferences. Helix boundary residues (the first and last helical residues) are called Ncap and Ccap at the N- and C-terminus, respectively.
http://www.cryst.bbk.ac.uk/PPS2/course/section8/ss-960531_9....
Claudia Coja Feb 7, 2014:
Ioana incerc niste deductii - mai mult sau mai putin logice:))
In aceasta lucrare apare: "...at the N terminal end (N-cap)..." de unde inteleg ca "N terminal end" si "N-cap" sunt acelasi lucru.
http://www.deepdyve.com/lp/elsevier/sheet-capping-signals-th...
Apoi:
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) refers to the start of a protein or polypeptide terminated by an amino acid with a free amine group (-NH2).
http://en.wikipedia.org/wiki/N-terminus
Dupa logica aceasta, raspunsul ar fi " N terminus" sau "amino-terminus"
Metodele sunt utilizate în biochimie și in biologia celulei. Sinteza are la bază cuplarea grupării carboxil -COOH (carbon terminus) cu gruparea -amino -NH2 (segmentul N terminus).
"... dacă se termină cu gruparea amino, devine amino-terminus (N-terminus).
http://www.google.de/url?sa=t&rct=j&q=&esrc=s&source=web&cd=...
Ioana Huiban (asker) Feb 7, 2014:
N-capped Am citit si eu acea postare si intr-adevar, intr-un context similar apare end-capped. Dar in restul documentului apare "N-capped" (mai exact de 7 ori). De asta am nevoie de ajutorul vostru :)
Claudia Coja Feb 7, 2014:
Silanizat Acelasi termen a fost tradus in poloneza. http://www.proz.com/kudoz/english_to_polish/medical:_pharmac... Din discutii reiese ca, de fapt, s-ar putea sa fie vorba de "end-capped".
Daca este vorba de end-capped, atunci ar putea fi "silanizat" :
Datorită volumului mic al grupării trimetilsilil, aceşti adsorbanţi sunt practic total silanizaţi (end-capped).
http://cachescan.bcub.ro/2008_05_28/cap_6_1_pag_90_104.pdf

Proposed translations

2 hrs
Selected

N- terminus/Amino terminus

Cf. discutiilor.
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4 KudoZ points awarded for this answer. Comment: "Multumesc Claudia!"
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