Glossary entry

Polish term or phrase:

działanie kompetycyjne antagonistyczne

English translation:

competitive antagonist

Added to glossary by Iwona Gandor
Dec 19, 2017 09:12
6 yrs ago
Polish term

działanie kompetycyjne antagonistyczne

Polish to English Medical Medical: Pharmaceuticals
Flumazenil jest benzodiazepiną o działaniu kompetycyjnym antagonistycznym na receptor benzodiazepinowy

opis działania leków odwracających sedację po zabiegu

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Discussion

geopiet Dec 19, 2017:
an action producing competitive antagonism A neutral antagonist does not affect the equilibrium between R and R*, but only prevents the binding of agonist to the receptor, thus producing competitive antagonism. - https://goo.gl/6qEi7j

Proposed translations

+3
42 mins
Selected

competitive antagonist

Tu użyłbym takiego zwrotu, np. flumazenil is a competitive antagonist of benzodiazepine receptor...

Por. https://en.wikipedia.org/wiki/Receptor_antagonist
https://www.ncbi.nlm.nih.gov/pubmed/2899985
https://www.ncbi.nlm.nih.gov/pubmed/8541433
Note from asker:
dziękuję
Peer comment(s):

agree Izabela Czartoryska
1 hr
Dziękuję!
agree Frank Szmulowicz, Ph. D.
1 hr
Dziękuję!
agree Marcin Pustkowski
3 hrs
Dziękuję!
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4 KudoZ points awarded for this answer. Comment: "dziękuję"
35 mins

antagonist mechanism of action

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Note added at 41 mins (2017-12-19 09:54:08 GMT)
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Flumazenil (also known as flumazepil, code name Ro 15-1788) is a selective benzodiazepine receptor antagonist available by injection and intranasal. It has antagonistic and antidote properties to therapeutically used benzodiazapenes, through competitive inhibition. - https://en.wikipedia.org/wiki/Flumazenil

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What is flumazenil's mechanism of action?

Flumazenil is a competitive antagonist of benzodiazepines at the GABAA receptor. - https://goo.gl/jZ7rix
Note from asker:
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